臨床診斷/藥物研發(fā)
臨床診斷方法必須具備穩定、準确的性質，并可靈敏檢出痕量或超痕就到量目标物。BPCL超微弱發(fā)光測量儀靈敏度高、穩定性好(hǎo)，已土中被(bèi)多家科研院校、醫院或檢測機構應用于臨床診斷技術的開(kā南山i)發(fā)研究中。同時(shí)BPCL超微弱發(fā)光測量儀可快速、靈敏、動态獲取發(fā)光動力學(x的習ué)曲線，這(zhè)一特點對(duì)研吧服究伴随著(zhe)發(fā)光現象的生命過(guò)程及評價科業藥物的抗氧化性至關重要。BPCL超微弱發(fā)光測量儀在臨床診斷及藥物研發(fā)應用中的例子大男有：
[1] Yang L L, Tao Y Z,嗎影 Yue G Y, Li R 人唱B.; Qiu, B, Guo L 愛那H, Lin Z Y, Yang H H. Hi雪好ghly selective and sensitive e外拿lectrochemilumine機草scence biosensor for p53 DNA 作風sequence based on nicking東車 endonuclease assisted target recycling們用 and hyperbranched rolling紙街 circle amplifica會著tion. Analytical chemistry, 2017, 88(10): 5097-生市5103.
[2] Zha可的ng S P, Zang L L, Zhang X Z, Dai 城放H, Xu G, Zhang Q暗書 R, Yang C P, Lin Y Y. Signal-o呢路n
electrochemiluminescent呢在 immunosensor based on poly (amidoam技信ine) dendrimer f道多unctionalized carbon nanodots am廠對plification for ultra能火sensitive detection 綠舞of α-fetoprotein. Electrochimica Ac鄉去ta, 2016, 196:67-74.
[3] Liu Y M, Mei L, Liu L J, Pen村銀g L F, Chen Y H, Ren S W. Sensitive ch妹關emiluminescence immunoassay by capi理友llary electrophoresis w時離ith gold nanoparticles.懂離 Analytical Chemistry, 2011, 83(3):1137-1143.
[4] Zhang Q R, Dai H, W船窗ang T, Li Y L, Zhang, S P, Xu G F, Ch匠視en S H, Lin Y Y. Ratiometric electrochemiluminescen服如t immunoassay for tumor marker re下路gulated by mesocrystals and biomimeti雜厭c catalyst. Electrochimica A雨時cta, 2016, 196: 565-571.
[5] He Y Z, Wang X X, Zh很車ang Y Z, Gao F, L影但i Y X, Chen H Q, Wang L. An ultr匠媽asensitive chem是員iluminescent immunosensor 愛分for the detection of 購冷human leptin using hemin/G-quadru筆錢plex DNAzymes-assembled signal ampl道歌ifier. Talanta, 2013, 116: 816-82技飛1.
[6] Shi G F, Cao J, 拿微Zhang J J, Huang媽學 K J, Liu Y M, Chen Y H, Ren S W我我. Aptasensor based on tripetalous ca有喝dmium sulfide-graphe鄉小ne electrochemiluminescence for the空厭 detection of carcinoemb木通ryonic antigen. Analyst, 2014, 139(22): 區輛5827-5834.
[7] Ding X P, Wang匠看 X T, Chen L L, Qi J, Xu T, Yu B 作讀Y. Quality and antioxida哥動nt activity detection of Crataegus 商女leaves using on-line high-perfo媽美rmance liquid chromatog地店raphy with diode array detector 看計coupled to chemiluminescence 開得detection. Food Chemistry, 2010, 120(3): 929-93電話3.
[8] Wu L, Ding X P,街白 Zhu D N, Yu B Y, Yan Y麗冷 Q. Study on the radical scave一雨ngers in the traditional Chinese medi風熱cine formula Shengmai S暗現an by HPLC–DAD coupled with chem紅不iluminescence (CL) and ESI–MS/MS.新很 Journal of Pharmaceu河城tical and Biomedic理制al Analysis, 2010, 52(4): 438-445.
[9] Huang X, Zhou Y H, Ma M H, C美慢ai Z X, Li T. Che兵匠miluminescence evaluation of anti內算oxidant activity and prevention of DNA 唱化damage effect of peptides isolate關個d from soluble eggshell membrane pr玩務otein hydrolysate. Journal of Agricultural & F說老ood Chemistry, 2010, 58(23):12妹訊137-12142.
[10] Zhou Z L, Yin W Q, Zhang H L, Fe紙行ng Z C Xia J M. A new iridoid glycoside綠到 and potential MRB inhibi如生tory activity of isol水少ated compounds from the呢習 rhizomes of Cyperus rotu爸服ndus L. Natural Product Research, 2013, 27(19): 1732-1736.場銀
[11] Fu H F, Xie B J, Gang F, et al. 樹日Effect of esteri森又fication with fatty熱麗 acid of β-cryptoxanthin on its thermal stabi請一lity and antioxidant activity by chemil森放uminescence method. Food Chemistry, 2010, 122(3): 602-609.
[12] Huang X, Zhou Y H, Ma M城動 H, Cai Z X, Li T. Che些員miluminescence eval時司uation of antiox新呢idant activity and prevention of DNA da窗聽mage effect of peptides isolate業多d from soluble 她些eggshell membrane protein hydrolysat光裡e. Journal of Agricultural & F服外ood Chemistry, 2010, 58(23): 12137-121金姐42.